Standardization of herbal formulation is essential in order to assess the quality of drugs. The present paper reports preparation and standardization of a herbomineral formulation which contains Zingiber officinalis (rhizome), Piper longum (fruit), Piper nigrum (fruit), Emblica officinalis (fruit,seed), Terminalia chebula (mature fruit), Terminalia belerica (pericarp of ripe fruit), Piper retrofractum (stem), Coriander sativum (fruit), Cuminum cyminum (fruit), Mercury, sulphur, loh bhasam, abharak bhasam. This Ayurvedic formulation is used to treat cold and cough. Here we discussed and focused about Morphology, Microscopy, Total ash, Acid insoluble ash, Water soluble and Alcohol soluble extractive value, bulk density, tapped density, Carr’s index, Hausner ratio, phytochemical tests, and Thin layer chromatography (TLC) etc. These parameters are required for authentication of any herbal drug and its Herbo-mineral formulation.