The present study is an attempt to investigate the angiogenic property of ethanolic leaf extract of Achyranthus aspera by in vitro, Hen's Egg Chorioallantoic Membrane method (HET-CAM). Ethanolic leaf extract of Achyranthus aspera treated CAM showed increased density of new blood capillaries as compared with control group treated with 0.9% Nacl. The results obtained in this study suggest that the Achyranthes aspera leaf extract revealed a significant scope to develop a novel broad spectrum of herbal formulations for wound healing and different herbal formulations