Plants have been used in ethno-medicine since many years and there has been an increasing interest in medicinal plants and their traditional use. The present study compared efficacy of Ampucare with that of silver sulfadiazine in partial thickness burn in rats. Adult male Sprague_Dawley rats were divided into three groups: control group (Normal saline treated group, Ampucare treated group and Silver sulfhdiazine treated group. Complete healing of burn wound was observe in all the animals. A significant decrease in wound size was observed in Ampucare treated and Silver sulfadiazine treated group as compared to contraol group on day 14. Both in control group and Silver sulfadiazine treated group not a single animal showed complete healing of the wound on day 14. Results suggested that Ampucare is significantly effective in treatment of partial thickness burn wounds than silver sulfadiazine.