Plant kingdom harbours an inexhaustible source of active ingredients valuable in the management of many intractable diseases. Phytochemical techniques played a significant role in searching raw materials and resources for pharmaceutical industry. The plant material was dried in shade, crushed and subjected to prepare different sequential extracts using soxhlet apparatus. Phytochemical screening of various extracts of Operculina turpethum was carried out by employing standard methods for conducting Qualitative phytochemical analysis for studying the presence of active compounds like Alkaloids, Tannins, Saponins, Glycosides, Phenols, Flavonoids, sugars, Terpenoids and Steroids. Our findings of crude extracts of the plant revealed the presence of saponins, steroid, alkaloids, terpenoid, flavonoids, cardic glycosides. It equally ascertains the bioactive components in the plant, thus agreeing with the potential therapeutic significance of the plant as a natural source of drug development.