We report a case of 70 year old women with primary hypertension and trigeminal neuralgia of the right side of face. Hypertension was well controlled with one antihypertensive drug for long time which became uncontrolled after administrating Carbamazepine for trigeminal neuralgia. The adverse effects of carbamazepine include cardiac conduction abnormalities, aplastic anemia, bone marrow depression, congestive heart failure, peripheral edema. Hypertension has rarely been documented with therapeutic doses of carbamazepine. On admission the patient had blood pressure 180/110 mmHg, despite an antihypertensive therapy. Treatment with additional antihypertensive medication did not reduce her blood pressure. After discontinuation of Carbamazepine levels of blood pressure were normal. Therefore, we considered that resistant hypertension was induced by oral carbamazepine therapy.
Zylfije Hundozi, Nazmije Ibishi, Fisnik Jashari and Nebih Musliu