Reach Us 44-7452-259145


Antiulcer And Antiinflammatory Activity Of Fresh Leave Extracts Of Polyalthia Longifolia In Rats

The present study was designed to investigate the antiulcer and anti-inflammatory potential of ethanolic extracts of Polyalthia longifolia and aqueous extracts of Polyalthia longifolia. Antiulcer activity was evaluated by pylorus ligation, aspirin induced and ethanolic induced ulcer models. Effect of concurrent administration of ethanolic and aqueous extracts of leaves extract Polyalthia longifolia at dose of 200 and 300 mg/kg b.w. respectively was given by oral route. Ethanolic and aqueous extracts of Polyalthia longifolia dose dependently decrease gastric content, total acidity, ulcer index, and increase in pH of gastric pylorus ligation ulcer model. Antiinflammatory activity was performed using Cotton pellet granuloma in rats. Ethanolic and aqueous extracts of higher dose (300 mg/kg) being the most active, exhibited maximum antiinflammatory activity. Extracts of Polyalthia longifolia may be useful as a natural antioxidant in the treatment of ulcer, inflammation and pain.

Author(s): Sharma RK, Mandal S, Rajani GP, Gupta N, Srivastava DP

Abstract | Full-Text | PDF

Share this  Facebook  Twitter  LinkedIn  Google+
30+ Million Readerbase
Recommended Conferences
Google scholar citation report
Citations : 7472

International Journal of Drug Development and Research received 7472 citations as per google scholar report

International Journal of Drug Development and Research peer review process verified at publons
Abstracted/Indexed in
  • Google Scholar
  • Genamics JournalSeek
  • China National Knowledge Infrastructure (CNKI)
  • CiteFactor
  • Scimago
  • Directory of Research Journal Indexing (DRJI)
  • WorldCat
  • Publons
  • MIAR
  • ResearchGate
  • University Grants Commission
  • Secret Search Engine Labs
  • Euro Pub

View More »

Flyer image


tempobet giriş

tempobet giriş

tipobet süpertotobet yeni adres süperbahis 747 güvenilir bahis siteleri telefonda sex sohbet

rolex replica