Analysis of Phytochemicals, Antibacterial and Antioxidant activities of Moringa oleifera Lam. Leaf extract- an in vitro study

The leading important things about utilizing plant-derived medication are relatively less dangerous than artificial drugs and provide deep restorative benefits. In this regard, Moringa oleifera plant was evaluated for its nutritional effects. The phytochemical study, antibacterial activity and the in vitro antioxidant activity of aqueous, chloroform and petroleum ether extracts of Moringa oleifera leaves were investigated. Phytochemical analysis revealed the presence of alkaloids, flavonoids, steroids, tannins, saponins and glycosides as major components. The Petroleum ether extracts of Moringa oleifera contains the high content of bioactive compounds such as phenol and flavonoids. The extracts were screened for in vitro antibacterial potential against enteric pathogenic bacteria such as Staphylococcus aureus, Pseudomonas aeruginosa, Salmonella typhi, E. coli and Vibrio cholera by disc diffusion method. Moringa oleifera showed potent antibacterial activity against several gram negative and gram positive bacteria. Antioxidants are shown to play an important position in your body immune system next to Reactive oxygen species (ROS). The enzymatic and non-enzymatic activities of SOD, Catalase, Peroxidase, Vitamin C, Carotenoids, and reduced Glutathione were high in petroleum ether extracts of Moringa oleifera. It shows high scavenging activity against DPPH, Nitrous Oxide and Hydroxyl Radical scavenging assays. As a result, Moringa oleifera possesses a good antioxidant, it has a scavenging property against ROS and also it has good antibacterial properties. Thus, Moringa oleifera can be used to synthesize a new drug preparation against various diseases responsible for severe illness.

Author(s): Malliga Elangovan, Dhanarajan. M. S, Rajalakshmi A, Jayachitra A, Pardhasaradhi Mathi, Narasimharao Bhogireddy

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