Abstract

A NORMATIVE STUDY OF NIGERIAN GROWN “MAHA-TITA” (KING OF BITTERS) - ANDROGRAPHIS PANICULATA NEES

The aim of the study is to characterize the aerial parts of Andrographis paniculata - an intensely bitter herb grown in Nigeria from seeds obtained in India. The ultimate aim is to develop a suitable dosage form from the herb for use in Nigeria. The bitterness value; various physicochemical characteristics; tests for key phytochemicals; and thin layer chromatography (TLC) were carried out on the air-dried herb as prescribed in relevant standard texts. The mean bitterness value for both men and women was 2.86 ± 1.74 x 103 units per g. The male value (2.07 ± 1.42 x 103) tended to be lower than the female?s (3.52 ± 1.82 x 103). The results of the physicochemical tests expressed in %w/w were: loss on drying (10.64 ± 0.36), total ash (14.10 ± 4.49), water extractability (30.37 ± 2.63) and acid insoluble ash (1.00 ± 0.06), which were similar to those reported for the Asian plant. The results of the macroscopic examination were also similar to those described in the literature for the Asian plant. The phytochemical tests reveal the presence of glycosides, saponins, tannins and alkaloids, but not of anthraquinones. Normal phase TLC of the drug yielded 5 spots as against 6 yielded by reverse TLC. The results provide useful quantitative and descriptive data that are essential for identifying and characterizing the Nigerian grown herb for pharmaceutical production.


Author(s): Ameh, Sunday; Obodozie, Obiageri; Inyang, Uford; Abubakar, Mujitaba; and Garba, Magaji

Abstract | Full-Text | PDF

Share this  Facebook  Twitter  LinkedIn  Google+

tempobet

tempobet giriş

tempobet giriş

tipobet süpertotobet yeni adres süperbahis 747 güvenilir bahis siteleri telefonda sex sohbet
https://wowcappadocia.com
https://cappadocia-hotels.com
https://balloon-rides.net

https://paperio-live.com

rolex replica

https://agario.red

https://naughtyworms.com

Vaporesso
Smok
https://www.unitedluxury.net/