Reach Us +44-7480-022449


Spherical Agglomeration Techniques and their Evaluation Parameters

Spherical agglomeration technique is a specialized and modern method which has been successfully employed to improve flowability, packability, Compressibility, wettability, solubility, and bioavailability of various poorly soluble and poorly Compressible drugs. The different Techniques discussed are Crystallization method, Solvent crystallization method, Quasi- emulsion diffusion method, Ammonia Diffusion method, neutralization method, and solvent agglomeration technique. This article gives a detailed and comprehensive review about different techniques, its advantages, mechanism and application of Spherical agglomeration Technique along with its Evaluation and Characterization methods. The spherical crystals can be Evaluated using FTIR (Fourier Transformation Infra red technique) DSC (Differential Scanning Calorimetry) X-ray Diffraction and Chromatographical methods. This technique also finds its application in improving taste of bitter drugs and in the preparation of nanospheres, microspheres and nano-particles.

Author(s): Soni Varinder, Rathore M S

Abstract | Full-Text | PDF

Share this  Facebook  Twitter  LinkedIn  Google+
30+ Million Readerbase
Flyer image
Abstracted/Indexed in
  • Chemical Abstracts Service (CAS)
  • Index Copernicus
  • Google Scholar
  • Genamics JournalSeek
  • China National Knowledge Infrastructure (CNKI)
  • CiteFactor
  • Scimago
  • Directory of Research Journal Indexing (DRJI)
  • WorldCat
  • Publons
  • MIAR
  • ResearchGate
  • University Grants Commission
  • Secret Search Engine Labs