The aim of the study is to cover the pharmacognostical and preliminary phytochemical screening of Zaleya govindia. The leaves of Zaleya govindia belonging to the family Aizoaceae is a widely grown plant throughout India. Pharmacognostical study included macroscopical characters, physico-chemical constants and fluorescence analysis. The powder characteristics showed presence of calcium oxalate crystals, starch grains, fibers, trichome, mucilage and lignified cells. Different ash values were determined to find the inorganic content in the sample. Physiochemical studies revealed, foreign matter (0.52±0.01w/w), total moisture content (Leaf-16.16%w/w), total ash (Leaf-23.5w/w%), acid insoluble ash (Leaf-5%w/w), water-soluble ash (Leaf-15%w/w), alcoholic soluble extractive value (Leaf-13.33%w/w), chloroform soluble extractive value (Leaf-5.33%w/w), petether soluble extractive value (Leaf-1.6%w/w), and water soluble extractive value (Leaf-32%w/w). Solvents of different polarity were used to find out the extractive value for leaf of Zaleya govindia. Carbohydrate, glycoside, alkaloid, flavonoids, tannin and resin compounds were found in preliminary phytochemical screening. Ultraviolet analysis exhibited considerable variation. Phytochemical investigation indicated the preparation of different extracts using different solvents and phytochemical tests for confirmation of the presence of carbohydrate, alkaloids, glycosides, triterpenes, phytosterols, phenolic compounds, tannin, saponins, and flavonoids. T.S of leaf with different reagents shows the presence mesophyll, spongy parenchyma, lower epidermis, lignin, lignified xylem, calcium oxalate crystals, collenchyma etc.