Sphaeranthus indicus Linn. (S. hirtus willd.) (SI) commonly called as East Indian Globe Thistle belonging to compositae (Hindi-mundi & Tamilkottakkarantai) which is widely distributed in India. The plant is used in traditional system of medicine in epilepsy, juice of the plant used in jaundice, hepatopathy and gastropathy. A parts of the herb mixed with oil is good for pruritus and painful swellings. The roots are bitter, acrid, sweet, thermogenic, diuretic, expectorant, febrifuge and stomachic. It is also useful in diabetes, hernia, haemorrhoids, helminthiasis and dyspepsia. Oil prepared by using the root is useful in scrofula. The powdered leaf is good for skin diseases and is considered as a nervine tonic. (Annonymouis, 1982; Chopra et al., 1956; Kirtikar and Basu, 1935). Phytochemical studies reported the presence of sesquiterpenes (Gogte et al., 1986), eudesmenolide and costic acid (Sohani Jayant et al., 1988), B-D-glucoside of (24 S)-24-ethylcholesta-5, 22-diene-3 B-ol (Singh et al., 1986), cyclopeptide alkaloids (Chughtai et al., 1992), 7-hydroxydesmonolides (Rajatkar and Nagasampagi, 1992), and Isoflavone glycoside (Yadava and Kumar, 1998). The pharmacological studies reported in this plant are antimicrobial activity (Singh et al., 1988), and immunostimulant activity of sesquiterpene glycoside (Shekhani et al., 1990). |
- Anonymous, 1982.Wealth of India, Raw materials, Publication and Information Directorate, CSIR, New Delhi. IV, 35-36.
- Chopra, R.N., Nayar, S.I., Chopra, I.C., 1956. Glossary of Indian Medicinal Plants, Publication and Information Directorate, New Delhi.p. 232.
- Kirtikar, K.R., Basu, B.D., 1935. Indian Medicinal Plant, II. Lalit Mohan Publication, Allahabad pp. 1347- 1348.
- Gogte, M.G., Ananthasubramanian, L., Nargund, K.S., Bhattcharya, S.C., 1986. Some interesting sesquiterpenoids from S. indicus Linn.(Compositae). Indian Journal of Chemistry 25B, 233-238.
- SohaniJayant, S., Rojatkar, Supada R., Kulkarni, Mandakini, M., DhaneshwarNarayan datta, N., Tavale, Sudam, S., Gururow, Tayur, N., Nagasampagi, Bhimsen, A., 1988.A new edudesmonolide and costic acid from S. indicus Linn. Journal of Chemical Society, Perkins Trans. 2, 157-160.
- Singh, S.K., Tripathi, V.J., Singh, A.K., Singh, R.H., 1989. ; - D-glucoside of (24 S)-24-ethylcholesta-5, 22-diene-3;-ol from S. indicus. Indian Drugs 26, 317-318.
- Chughtai, M.I.D., Khokhar, Irshad, Ahmed, Ashfaq. 1992. Isolation, purification and structural determination of alkaloids from the flowers of S. indicus. Sci International (Lahore), 4, 151-154.
- Rojatkar, S.R., Nagasampagi, B.A., 1992. 7- Hydroxyeudesmonolides from Sphaeranthusindicus. Phytochemistry 31, 3270-3271.
- Yadava, R.N., Kumar, S., 1998. A novel isoflavone glycoside from the leaves of Sphaeranthusindicus.Fitoterapia 70, 127-129.
- Singh, S.K., Saroj, K., Tripathi, V.J., Singh, A.K., Singh, R.H., 1988. Antimicrobial principle from Sphaeranthusindicus L. family Compositae. International Journal of Crude Drug Research 26, 235-239.
- Shekhani, M.S., Shah, P. M., Yasmin, A., Siddiqque, R., Perveen, S., Khan, K. M., 1990. Atta-ur-Rahman.An immunostimulentsesquiterpene glycoside from Sphaeranthusindicus.Phytochemistry 29, 2573- 2576.
- Donald, J., Ecobichon, 1997. The Basis of Toxicity Testing. CRC Press, New York, pp. 43–49.
- Goel, R.K., Chakrabarti, A., Sanyal, A.K., 1985. The effect of biological variables on the antiulcerogenic effect of vegetable plantain banana.PlantaMedica 2, 85-88.
- Shay, H., Komarov, S.A., Fels, S.E., Meraze, D., Gruenstein, M., Siplet, H.A., 1945. Simple method for the uniform production of gastric ulceration. Gastroenterology 5, 43-61.
- Ganguly, A.K., Bhatnagar, O.P., 1973. Effect of bilateral adrenalatomy on production of restraint ulcers in the stomach of albino rats.Canadian Journal of Physiology and Pharmacology 51, 748- 750.
- Kulkarni, S.K., 1999. Handbook of Experimental pharmacology, 3rd ed. VallabhPrakashan, New Delhi. pp. 148-150.
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