Serial No Group Dose (mg/kg) Paw volume after carrageenan inj. (ml) % Inhibition 1sthr 2ndhr 3rdhr 4thhr 1sthr 2ndhr 3rdhr 4thhr 1. Control (NS) ------ C1=0.16 C2=0.19 C3=0.17 C4=0.12 C5=0.14 C6=0.12 C1=0.21 C2=0.23 C3=0.20 C4=0.19 C5=0.22 C6=0.18 C1=0.24 C2=0.25 C3=0.24 C4=0.23 C5=0.26 C6=0.24 C1=0.29 C2=0.30 C3=0.28 C4=0.31 C5=0.30 C6=0.28 --- --- --- --- 2. Standard (Indomethacin) 10 S1=0.17 S2=0.14 S3=0.14 S4=0.15 S5=0.18 S6=0.13 S1=0.18 S2=0.13 S3=0.14 S4=0.13 S5=0.16 S6=0.11 S1=0.16 S2=0.11 S3=0.12 S4=0.11 S5=0.14 S6=0.09 S1=0.14 S2=0.09 S3=0.10 S4=0.09 S5=0.12 S6=0.07 0 33.3 50 66.7 3. Test (extract) 200 T1=0.16 T2=0.17 T3=0.12 T4=0.12 T5=0.14 T6=0.19 T1=0.20 T2=0.21 T3=0.19 T4=0.18 T5=0.21 T6=0.17 T1=0.22 T2=0.23 T3=0.22 T4=0.21 T5=0.24 T6=0.22 T1=0.25 T2=0.26 T3=0.24 T4=0.27 T5=0.26 T6=0.24 0 4.8 8.3 16.7 4. Test (extract) 500 T1T’=0.15 T2T’=0.16 T3T’=0.11 T4T’=0.11 T5T’=0.13 T6T’=0.18 T1T’=0.19 T2T’=0.20 T3T’=0.18 T4T’=0.17 T5T’=0.20 T6T’=0.16 T1T’=0.21 T2T’=0.22 T3T’=0.21 T4T’=0.20 T5T’=0.23 T6T’=0.21 T1T’=0.24 T2T’=0.25 T3T’=0.23 T4T’=0.26 T5T’=0.25 T6T’=0.23 6.7 14.3 12.5 20 5. Test (extract) 1000 T1”=0.18 T2’’=0.15 T3’’=0.15 T4”=0.16 T5”=0.19 T6”=0.14 T1”=0.19 T2’’=0.12 T3’’=0.15 T4”=0.12 T5”=0.17 T6”=0.12 T1”=0.17 T2’’=0.12 T3’’=0.13 T4”=0.12 T5”=0.15 T6”=0.10 T1”=0.15 T2’’=0.10 T3’’=0.11 T4”=0.10 T5”=0.13 T6”=0.10 6.7 28.6 45.8 63.3 Average paw volume after carrageenan inj. (ml) C=0.15 S=0.15 T=0.15 T’=0.14 T”=0.16 C=0.21 S=0.14 T=0.20 T’=0.18 T”=0.15 C=0.24 S=0.12 T=0.22 T’=0.21 T”=0.13 C=0.30 S=0.10 T=0.25 T’=0.24 T”=0.11

Table 2: Carrageenan induced paw edema technique (acute inflammation).