A series of 5-substituted-arylidene-3-substitutedbenzyl- thiazolidine-2, 4-dione derivatives were synthesized through Knoevenagel condensation and studied for their glucose lowering capability against alloxan induced diabetic rats. Some of the compounds showed appreciable antidiabetic activity comparable to standard drug rosiglitazone.
All Published work is licensed under a Creative Commons Attribution 4.0 International License
Copyright © 2019 All rights reserved. iMedPub LTD Last revised : July 20, 2019