In the present the phytochemical analysis of Sauropus androgynus was carried out. Phytochemical analysis of the leaves of this plant is reported for the first time. The leaves indicated the presence of proteins, resins, steroids, tannins, glycosides, reducing sugar, carbohydrates, saponins, sterols, terpenoids, acidic compounds, cardiac glycosides, catechol, phenols, alkaloids, flavonoids. In the GC-MS analysis the Sauropus androgynus extract result shows the presence of bioactive compounds which revealed a broad spectrum of many medicinal property and antioxidant activity were identified. The functional group present in these compounds was identified by IR spectral analysis. This study also helped to identify the formula and structure of biomolecules which can be used as drugs.