The present investigation was carried out to focus on the hypoglycemic effect of the leaves of Artocarpus heterophyllus in normal and streptozocin induced diabetic rats. The Plant was subjected to pharmacognostic, physico-chemical and phytochemical evaluations which will assist in standardization for authenticity, quality and identification of the herbal products. Treatment with extract of the leaves at dose 250 mg/kg to diabetic rats resulted in significant reduction of serum glucose, total cholesterol, whereas significant increased level of high density lipoprotein was observed.The present study clearly demonstrated that the plant is having potential hypoglycemic activity which may be beneficial for the management and treatment of diabetes mellitus.
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