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Abstract

Method development of Pioglitazone by UV Spectrophotometer

In the present research a simple, accurate, precise and cost effective UVVis spectrophotometric method for the estimation of Pioglitazone, in bulk and pharmaceutical dosage form was illustrated. The absorption maxima of the drug were found to be 234 nm in Methanol. A linear response was observed in the range of 02-12 μg/ml with a regression coefficient of 0.996. Validation parameters were carried out as per the guidelines of International Conference for Harmonization. This method can be used in the industries for determination of Pioglitazone to analyze the quality of formulation without interference of the excipients.


Author(s): Vijay VIkram Singh Partha Chaudhary Hema B Richa Tiwari

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