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Antibacterial and Free Radical Scavenging Activities of stem bark of Psidium guajava Linn

Psidium guajava has been widely used in traditional systems of medicine for a variety of diseases. In the present study, stem bark of Psidium guajava was evaluated for its antimicrobial and antioxidant activities. The agar disk diffusion method was used to study the antibacterial activity of ethanolic extract of stem bark of Psidium guajava (EPG) against Bacilus subtilis, Pseudomonas aeruginosa and Escherichia coli. Free radical scavenging assays such as 2, 2- diphenyl-1-picryl hydrazyl (DPPH) and nitric oxide radical scavenging assays were performed. The EPG showed antibacterial activity against all three bacterial stains. It was observed that the EPG effectively scavenged free radicals in a dose dependent manner and antioxidant activity was compared to standard antioxidant such as ascorbic acid

Author(s): Balakrishnan N, Balasubramaniam A, Nandi P, Dandotiya R and Begum S

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