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Abstract

A COMPARATIVE STUDIES OF THE ACTION OF GLUCOSE AND SCOPOLAMINE ON THE COGNITIVE FUNCTION OF ALBINO RATS USING DIGITAL ZERO MAZE APPARATUS

Objective: The Purpose of the Present study was to compare the action of glucose and scopolamine on the cognitive function using digital zero maze apparatus on albino rats.

Method: The digital zero mazes was made of ply-wood in which to arms positioned at right angled related to each other .This apparatus is like a digital zero maze digit in appearance. Albino rats were given a free exploration session consisting of 10 minutes in the apparatus 24 prior to testing to allow familition to the testing apparatus. Albino rat was treated with glucose to determine the memory performance in second trials scopolamine was injected and effect was observed.

Result: In the present study 2 groups were taken and had given treatment glucose and scopolamine (buscopan).The digital zero maze was design to study animal behavior after supervised training given to the rats the observation glucose and scopolamine were shows that the glucose a have some sought of cognition enhancing activity in experiment animals On the other hand the scopolamine slows down cognition activity of brain.

Conclusion: The result shows that glucose enhanced the activity while scopolamine slows down cognition activity of brain.


Author(s): Jain Deepak, Singh Vinay R., Verma Sofiya, Yadav Priyanka

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